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George Nicholas Papanicolaou was born in Kimi on the island of Euboea. It is near the southern town of Karystos known for the ancient physician Diokles of. Even at a young age, George Papanicolaou envisioned himself striving to live his life out on some large, important, but as yet undefined stage. After receiving his. Georgios Nikolaou Papanikolaou was a Greek pioneer in cytopathology and early cancer George Papanikolaou In he moved to Miami, Florida, to develop the Papanicolaou Cancer Research Institute at the University of Miami, but.

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George’s violin playing at restaurants and coffee-shops supplied them with a few extra cents. The history of the Papanicolaou smear and the odyssey of George and Andromache Papanicolaou.

The position he finally found and accepted was as the physiologist for a scientific expedition on an oceanographic research vessel sponsored by the Oceanographic Museum of Monaco and the Prince of Monaco.

George Nicholas Papanicolaou was a pioneer in elucidating the physiology and cytologic characteristics of the female reproductive system.

George Papanicolaou (–): Discoverer of the Pap smear

In total, Papanicolaou authored four books and over one hundred articles. Please login to access the full content.

He subsequently served as an assistant surgeon in the military until The institute was renamed the Papanicolaou Cancer Research Institute in his honor. Georgshe graduated from medical school with top honours. In he published another memorable geotge, the Atlas of Exfoliative Cytologythus creating the foundation of the modern medical specialty of cytopathology.


In Papanikolaou told an incredulous audience of physicians about the noninvasive technique of gathering cellular debris from the lining of the vaginal tract and smearing it on a glass slide for microscopic examination as a way to identify cervical cancer. Agriculture Armed forces and intelligence services Art and architecture Business and finance Education and scholarship. This resulted in a historic drop in the papaniicolaou of cervical cancer nichokas American women.

Miami, FloridaUS. The work that eventually resulted in his life-saving smear and test, began in when he began the study of sex chromosomes in guinea pigs. George Nicholas Papanicolaou Greek-American Physician G eorge Nicholas Papanicolaou was the originator of the Pap test used in the diagnosis of cervical cancer. National Center for Biotechnology InformationU. G eorge Nicholas Papanicolaou was the originator of the Pap test used in the diagnosis of cervical cancer.

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[George Nicholas Papanicolaou].

Atlas of Exfoliative Cytology. Cite this article Pick a style below, and copy the text for your bibliography. George Nicholaus Papanicolaou [online] [Accessed February 19, ]. As a boy he loved outdoor life, particularly mountain hiking av boating.

After serving for two years as second lieutenant in the medical corps of the Greek army during the Balkan War, fighting the Turks, he visited the United States, and when World War I broke out inhe decided to stay there.

George Papanicolaou, the father of modern cytology. University of Athens University of Munich. Papanicolaou’s studies in clinical cytology were reinforced by new ways of examining disease in general, and by specific medical breakthroughs.


The Pap smear Papanicolaou is best known for his development of the “Pap test,” for the cytologic diagnosis of cancer, especially cancer of the uterus – second only to the breast as the site of origin of fatal cancers in American women. Dedication of the Papanicolaou Cancer Research Institute. Please review our privacy policy. Papanicolaou and Traut argued that cancerous cervical lesions could be detected by observable and measurable cellular changes while the cells were still in a preinvasive phase.

Thus what was probably the first Pap smear — from a guinea pig. These outcasts were socially isolated, and Papanicolaou gave them both medical and personal care with compassion and grace.

In an attempt to test his theories in humans, Papanicolaou undertook a study of human vaginal smears. The test was an important milestone in medicine because it reliably discerned the earliest and most curable stage of cancer. The first National Cytology Congress, held inhailed this new diagnostic tool for carcinoma of the cervix as unique because it could detect cancer before it was visible.

Papanicolaou persisted with his ideas, and finally cytologic examination of the cervix was accepted.